Chondroid syringoma of the upper lip: a rare case highlighting diagnostic challenges and literature review.

Chondroid syringoma is a rare benign cutaneous adnexal tumor, most commonly found in the head and neck region. Its occurrence on the upper lip is exceptional. We report a case involving a 63-year-old man presenting with a painless, firm swelling of the left upper lip that gradually enlarged over three years. Clinical examination revealed a 1.6 cm submucosal nodule. Surgical excision with a 3 mm margin and direct closure using 5-0 Vicryl Rapide sutures was performed. Histopathological and immunohistochemical analysis confirmed the diagnosis of chondroid syringoma. No recurrence or functional/aesthetic complications were observed during 12 months of follow-up. This report underscores the diagnostic difficulties posed by this rare location, discusses differential diagnoses with other adnexal and salivary gland tumors, and reviews management considerations based on current literature.