Effect of Polynucleotides on Apex Lingual Regeneration After Amputation Due to a Car Accident: A Case Report.

The tongue is an essential organ for swallowing food, speaking, and even breathing. Due to medical reasons or traumatic accidents, the partial loss of this organ can severely affect the quality of life of patients. The tongue has a remarkable capacity for endogenous regeneration. In this case report, the effect of polynucleotides (PDRN) on stimulating tissue regeneration and healing was studied. A relevant recovery in phonemic pronunciation and a reduction in the formation of fibrotic tissue in the scar were observed. These results suggest that PDRN may be a safe and effective adjuvant for promoting natural tongue regeneration.