Journal of applied oral science : revista FOB · 2011
In vitro adherence of Candida albicans isolated from patients with chronic periodontitis.
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Machado Adriana Gadotti, Komiyama Edson Yukio, Santos Silvana Soléo Ferreira Dos, Jorge Antonio Olavo Cardoso, Brighenti Fernanda Lourenção, Koga-Ito Cristiane Yumi
Аннотация
UNLABELLED: Adherence is considered an extremely important virulence factor in yeast.
OBJECTIVE: The aim of this study was to analyze the adherence to epithelial cells of C. albicans isolated from patients with chronic periodontitis in comparison to healthy patients.
MATERIAL AND METHODS: Candida albicans cells isolated from individuals with chronic periodontitis (n=25) and healthy controls (n=25) were included in this study. Suspensions of C. albicans (10(6) cells/mL) and epithelial cells (10(5) cells/mL) were mixed and incubated at 37ºC for 1 h. The number of yeasts adhered to 25 epithelial cells was counted.
RESULTS: The number of C. albicans cells adhered to epithelial cells was statistically higher in the chronic periodontitis group than in the control group (Student's t-test, p=0.000).
CONCLUSION: The results of the present study suggest a higher Candida adherence of samples isolated from patients with chronic periodontitis.
OBJECTIVE: The aim of this study was to analyze the adherence to epithelial cells of C. albicans isolated from patients with chronic periodontitis in comparison to healthy patients.
MATERIAL AND METHODS: Candida albicans cells isolated from individuals with chronic periodontitis (n=25) and healthy controls (n=25) were included in this study. Suspensions of C. albicans (10(6) cells/mL) and epithelial cells (10(5) cells/mL) were mixed and incubated at 37ºC for 1 h. The number of yeasts adhered to 25 epithelial cells was counted.
RESULTS: The number of C. albicans cells adhered to epithelial cells was statistically higher in the chronic periodontitis group than in the control group (Student's t-test, p=0.000).
CONCLUSION: The results of the present study suggest a higher Candida adherence of samples isolated from patients with chronic periodontitis.