Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2008
[Healing efficacy of repairing mucosa defect with heterogeneity acellular dermal matrix].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Sun Yan, Zhang Qingquan, Song Xicheng, Chen Xiumei, Zhang Hua, Wang Qiang, Wang Yan
Аннотация
OBJECTIVE: To introduce the clinical application of heterogeneity (cattle) acellular dermal matrix (ADM) in the repair of mucosa defect otolaryngology.
METHODS: From October 2006 to March 2007, 12 cases of mucosa defect was repaired with heterogeneity ADM after the surgery. There were 10 males and 2 females, aged 18-76 years. Defect was caused by deflection of nasal septum in 1 case, melanoma of front and midst basalis (capillary hemangioma) in 1 case, nasal vestibule angioma (T2N2M0) in 1 case, cancer of hypopharynx (T2N1M0) in 1 case, cancer of amygdale in 3 cases (2 of T2N0M0 and 1 of T3N1M0), cervical segments esophageal carcinoma in 1 case, and cancer of larynx in 4 cases (3 of T2N0M0 and 1 of T3N1M0).
RESULTS: All these 12 cases were followed up for 6 months. The results of endoscope showed that heterogeneity ADM mingled with mucosa within 3 months after operation and the function was recovered. Pharynx fistula occurred in 1 case of hypopharynx cancer after the operation. After treatment of dressing change and antibiotics for 10 days, the wound healed, but after 2 months tumor recurred. All the patients were treated by radiation treatment. One case of amygdala cancer recurred and transferred to the neck after 2 months of radiation treatment. But 1 case of hypopharynx cancer died of massive haemorrhage after radiation treatment for 3 months.
CONCLUSION: Heterogeneity ADM can be easily obtained and it is a new method to repair mucosa defect. The operative procedure is easy to perform and worthwhile to be applied to clinical operation.
METHODS: From October 2006 to March 2007, 12 cases of mucosa defect was repaired with heterogeneity ADM after the surgery. There were 10 males and 2 females, aged 18-76 years. Defect was caused by deflection of nasal septum in 1 case, melanoma of front and midst basalis (capillary hemangioma) in 1 case, nasal vestibule angioma (T2N2M0) in 1 case, cancer of hypopharynx (T2N1M0) in 1 case, cancer of amygdale in 3 cases (2 of T2N0M0 and 1 of T3N1M0), cervical segments esophageal carcinoma in 1 case, and cancer of larynx in 4 cases (3 of T2N0M0 and 1 of T3N1M0).
RESULTS: All these 12 cases were followed up for 6 months. The results of endoscope showed that heterogeneity ADM mingled with mucosa within 3 months after operation and the function was recovered. Pharynx fistula occurred in 1 case of hypopharynx cancer after the operation. After treatment of dressing change and antibiotics for 10 days, the wound healed, but after 2 months tumor recurred. All the patients were treated by radiation treatment. One case of amygdala cancer recurred and transferred to the neck after 2 months of radiation treatment. But 1 case of hypopharynx cancer died of massive haemorrhage after radiation treatment for 3 months.
CONCLUSION: Heterogeneity ADM can be easily obtained and it is a new method to repair mucosa defect. The operative procedure is easy to perform and worthwhile to be applied to clinical operation.