Gan to kagaku ryoho. Cancer & chemotherapy · 2007
[A case of recurrent gastric cancer with peritoneal dissemination--prolonging life and good QOL by chemotherapy with combined use of paclitaxel].
Клинический случайАннотация на английскомСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Hayashi Yuko, Akiyama Junichi, Watanabe Mika, Nozaki Yuichi, Iwashita Ryouko, Nagaoki Yuko, Sakurai Toshiyuki, Oshima Takao, Nagata Naoyoshi, Yago Yuzou, Sako Akahito, Kobayakawa Masao, Tamegai Yoshirou, Masaki Naohiko, Uemura Naomi, Umeda Noritsugu
Аннотация
A 55-year-old man with advanced gastric cancer underwent total gastrectomy (T3N0M0, stage II , por, sig) in the USA. Following his return to Japan, the patient then suffered from a recurrence with ileus, bilateral hydronephrosis and ascites caused by peritoneal dissemination. Systemic chemotherapy of paclitaxel combined with 5-FU was performed, and after four cycles, ileus, bilateral hydronephrosis and ascites disappeared. S-1 monotherapy was started to maintain his QOL, but after five cycles, ileus of the transverse colon recurred. Colostomy was performed and systemic chemotherapy of paclitaxel combined with S-1 was performed. For 13 months, the patient's condition remained stable and he returned to society, but died 30 months after the first recurrence. This case suggests that paclitaxel-based chemotherapy is a promising treatment for gastric cancer with peritoneal dissemination.