Effect of allogenic demineralized dentin matrix vs. xenograft in maxillary sinus floor augmentation: A randomized split-mouth study.

INTRODUCTION

Maxillary sinus floor augmentation (MSFA) is commonly required in posterior maxillary atrophy. This study compared allogenic demineralized dentin matrix (ADDM) with a xenograft in MSFA.

METHODS

In this randomized split-mouth trial, nine patients underwent bilateral MSFA with ADDM on one side and a xenograft on the other. Cone-beam computed tomography (CBCT) was used to assess bone height and density at baseline and at six months. Core biopsies were obtained for histologic analysis.

RESULTS

Both groups showed significant increases in bone height and density (P<0.001). Mean bone density gain was 618.65±232.20 HU (ADDM) vs. 540.87±238.02 HU (xenograft, P=0.49). Mean bone height gain was 9.34±1.38 mm (ADDM) vs. 9.12±1.13 mm (xenograft, P=0.724). Histology showed viable new bone, with ADDM exhibiting higher collagen fiber density and vascularization.

CONCLUSION

ADDM showed clinical, radiographic, and histological outcomes comparable to xenograft in MSFA, suggesting its potential as a viable alternative.