Journal of conservative dentistry and endodontics · 2024
Comparative analysis of remineralizing efficacy of strontium-doped bioactive glass, BioMin, and NovaMin containing dentifrice on artificial white spot lesions after chlorhexidine pretreatment - An in vitro study.
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Nandhini G, Samraj Jemima Shalini, Anish S Mohamed, Ramachandran Anil Kumar, Nirmala Chandrasekaran, Denis G F Luke
Аннотация
AIM: This study aimed to compare the remineralizing efficacy of strontium-doped bioactive glass, BioMin, and NovaMin containing dentifrices on artificial white spot lesions (WSLs) after chlorhexidine (CHX) pretreatment using energy-dispersive X-ray analysis (EDAX).
MATERIALS AND METHODOLOGY: Twenty-four samples of maxillary first premolars extracted for orthodontic purposes were selected. Artificial WSLs were produced by immersing the samples in a prepared demineralizing solution for 3 days. All the samples were pretreated with CHX and divided into four groups and six samples each. Group A treated with strontium-doped bioactive glass, Group B with BioMin, Group C with NovaMin, and Group D with artificial saliva as the control group for 14 days. pH-cycling model was used to simulate the oral cavity changes. EDAX was used to record the values at baseline, demineralization, and after remineralization.
STATISTICAL ANALYSIS: Data were analyzed using one-way ANOVA (post hoc), followed by unpaired t-test and Scheffe tests with Statistical Package for the Social Sciences version 16.
RESULTS: Strontium-doped bioactive glass exhibited a greater mineral regain compared to BioMin, NovaMin, and control groups.
CONCLUSION: Strontium-doped bioactive glass has enhanced mineral deposition on carious teeth and may provide an alternative clinical strategy for remineralizing early enamel lesions.
MATERIALS AND METHODOLOGY: Twenty-four samples of maxillary first premolars extracted for orthodontic purposes were selected. Artificial WSLs were produced by immersing the samples in a prepared demineralizing solution for 3 days. All the samples were pretreated with CHX and divided into four groups and six samples each. Group A treated with strontium-doped bioactive glass, Group B with BioMin, Group C with NovaMin, and Group D with artificial saliva as the control group for 14 days. pH-cycling model was used to simulate the oral cavity changes. EDAX was used to record the values at baseline, demineralization, and after remineralization.
STATISTICAL ANALYSIS: Data were analyzed using one-way ANOVA (post hoc), followed by unpaired t-test and Scheffe tests with Statistical Package for the Social Sciences version 16.
RESULTS: Strontium-doped bioactive glass exhibited a greater mineral regain compared to BioMin, NovaMin, and control groups.
CONCLUSION: Strontium-doped bioactive glass has enhanced mineral deposition on carious teeth and may provide an alternative clinical strategy for remineralizing early enamel lesions.