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Rehabilitation oncology (American Physical Therapy Association. Oncology Section) · 2017

Feasibility and functional outcomes of children and adolescents undergoing preoperative chemotherapy prior to a limb-sparing procedure or amputation.

СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Corr Angela Meyer, Liu Wei, Bishop Michael, Pappo Alberto, Srivastava Deo Kumar, Neel Michael, Rao Bhaskar, Wilson Terry, Ness Kirsten K

Аннотация

BACKGROUND: Survivors of lower extremity (LE) malignancies experience functional deficits.

PURPOSE: The purpose of this prospective clinical trial was to determine feasibility and functional outcomes of adding pre-habilitation during the 10-12 week period prior to a planned surgery to remove the tumor in children and adolescents with a LE sarcoma.

DESIGN: Pilot study.

SETTING: St. Jude Children's Research Hospital (SJCRH).

PATIENTS: Participants included 14 individuals between the ages of 8 and 20 years who were diagnosed with a LE sarcoma. Participant outcomes were compared to a control group of 35 individuals treated for osteosarcoma that obtained the same functional assessments but no pre-habilitation.

INTERVENTION: The intervention group received strengthening exercises and mobility training 3 times per week for 30-60 minutes for 10-12 weeks preoperatively.

MEASUREMENTS: Participants completed the Functional Mobility Assessment (FMA) and measures of strength and range of motion (ROM) of bilateral lower extremities (BLEs) at baseline, after 10-12 weeks of preoperative PT, and at 20-22 weeks.

RESULTS: Twelve participants completed at least 50% of their schedule pre-habilitative sessions. The intervention group scored significantly better on the FMA than the control group at weeks 20-22 (35.6 vs. 25.7, p .0267). No significant difference was found in ROM or strength.

LIMITATIONS: Due to this study being a pilot study, the sample size was small. Therefore, we cannot infer generalizability.

CONCLUSIONS: Findings suggest that those diagnosed with a LE malignancy awaiting a limb sparing procedure or amputation participate in at least 50% of scheduled PT sessions and benefit from them.

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

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