British journal of urology · 1995
Treatment of catheter-associated Candiduria with fluconazole irrigation.
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Simşek U, Akinci H, Oktay B, Kavrama I, Ozyurt M
Аннотация
OBJECTIVE: To examine the safety and efficacy of fluconazole in patients with a permanent nephrostomy or suprapubic catheter in the prevention of candiduria.
PATIENTS AND METHODS: Twenty patients with a nephrostomy or suprapubic catheter who had at least two positive urine cultures with a minimum of 15,000 col/mL Candida counts were studied. The catheters were irrigated with fluconazole solution prepared as 1 mg/mL with normal saline. Repeated urine cultures were obtained.
RESULTS: In 17 patients Candida was eradicated from the urine by the third to sixth day of irrigation. No side-effects were noted.
CONCLUSION: Fluconazole as an irrigant is effective and safe in the treatment of catheter-associated candiduria, which can be eliminated without changing the catheter.
PATIENTS AND METHODS: Twenty patients with a nephrostomy or suprapubic catheter who had at least two positive urine cultures with a minimum of 15,000 col/mL Candida counts were studied. The catheters were irrigated with fluconazole solution prepared as 1 mg/mL with normal saline. Repeated urine cultures were obtained.
RESULTS: In 17 patients Candida was eradicated from the urine by the third to sixth day of irrigation. No side-effects were noted.
CONCLUSION: Fluconazole as an irrigant is effective and safe in the treatment of catheter-associated candiduria, which can be eliminated without changing the catheter.