Incidence and risk factors for early transient intraocular pressure elevation after penetrating canaloplasty in patients with glaucoma.

BACKGROUND

This study aimed to evaluate the incidence and risk factors for early transient intraocular pressure (IOP) elevation after penetrating canaloplasty (PCP) in patients with primary open-angle glaucoma (POAG), primary angle-closure glaucoma (PACG) and secondary glaucoma (SG).

METHODS

This retrospective study included 198 eyes of 198 patients with glaucoma. Participants were classified as normal IOP, early transient high IOP (E-HIOP [Tst]), early persistent IOP elevation, late transient high IOP, and late persistent IOP elevation, based on the period and persistence of postoperative IOP elevation.

RESULTS

E-HIOP (Tst) developed in 34.8%, 33.3%, and 40.9% of eyes with POAG, PACG, and SG, respectively. In comparison with normal IOP group, we observed the following variations in E-HIOP (Tst) cohorts: 8 - 10 years younger in patients with POAG and PACG; higher prevalence of hyphema (45.5% vs. 20.5%) in POAG; higher baseline IOP in PACG and SG (7 - 8 mmHg); higher preoperative IOP maximum (IOPpre-max) in SG (all p < 0.05). Higher IOPpre-max was a risk factor for E-HIOP (Tst) in PACG and SG (p < 0.05).

CONCLUSIONS

Nearly 30 - 40% of eyes developed E-HIOP (Tst) after PCP. E-HIOP (Tst) tended to develop in younger participants and those with higher preoperative IOP. A higher IOPpre-max was a risk factor for E-HIOP (Tst) in PACG and SG.