Heliyon · 2024
Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative study.
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Cervella Lorena L, García Oro Cecilia, Fantilli Anabella C, Di Cola Guadalupe, Martínez Wassaf Maribel G, Oropeza Gabriela, Castro Gonzalo M, Sicilia Paola, Ré Viviana E, Pisano Maria Belén
Аннотация
In Argentina, circulation of hepatitis E virus (HEV) genotype 3 has been described, producing sporadic cases of acute and chronic hepatitis. Limited information is available regarding HEV infection in children, so we aimed to investigate this virus in a pediatric population from the country. Serum samples from Argentine children (0-18 years old) (n = 213) were studied for IgG anti-HEV, IgM anti-HEV and RNA-HEV: 202 samples belonged to individuals attending health-care centers for routine check-ups, and 11 samples from patients with acute hepatitis of unknown etiology. Seropositivity for IgG anti-HEV was 1.49 % (3/202). One sample from an 18-years-old female patient with acute hepatitis tested positive for IgM anti-HEV detection, negative for IgG anti-HEV and RNA-HEV, but also positive for IgM anti-EBV. The HEV prevalence was low and showed circulation among children in central Argentina.