[Ultrastructural changes of gastric superficial epithelium cells in chronic Helicobacter gastritis].

Electron-microscopic investigations were carried out in 22 specimens of biopsy material from pyloric and fundal parts of the stomach in patients with chronic Helicobacter gastritis. In 6 cases of normal mucosa Helicobacter pylori (HP) was absent both in the antrum and fundus. In chronic antral gastritis HP was found in both regions. Variants of HP adhesion to the epithelium and its interactions were studied. It is demonstrated that HP may penetrate into intercellular spaces and cell cytoplasm. Cell reciprocal reaction to adhesion and invasion was accompanied by hyperplasia of the microvilli, clasmatosis and "selfsanation" phenomenon. Differences between ultrastructural changes in the antrum and fundus were considered.