European review for medical and pharmacological sciences · 2003
Protein profile of Helicobacter pylori strains by isoelectrofocusing in patients affected by chronic gastritis.
Клиническое исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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История · было → стало
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Barbaro S Paparo, Petrigni G, Giovannelli F, Cerroni Fabio, Caroselli A, De Rosa R, Caroselli C
Аннотация
BACKGROUND: To understand if relapse, following antimicrobial treatment was due to re-infection or to recrudescence.
METHODS: Fifty patients with dyspepsia were studied prospectively. They were followed up by endoscopy and biopsy of antral mucosa before and after treatment with anti-microbial therapy. Gel isoelectrofocusing was used to characterize protein profile of Hp.
RESULTS: At baseline 40 patients were affected by chronic gastritis associated with Hp. At the end of treatment 75% patients given omeprazole, amoxicillin and clarithromycin were Hp infected: 43% showed the same protein profile and 57% different.
CONCLUSIONS: Our data suggest that the relapse is due to recrudescence or to reinfection.
METHODS: Fifty patients with dyspepsia were studied prospectively. They were followed up by endoscopy and biopsy of antral mucosa before and after treatment with anti-microbial therapy. Gel isoelectrofocusing was used to characterize protein profile of Hp.
RESULTS: At baseline 40 patients were affected by chronic gastritis associated with Hp. At the end of treatment 75% patients given omeprazole, amoxicillin and clarithromycin were Hp infected: 43% showed the same protein profile and 57% different.
CONCLUSIONS: Our data suggest that the relapse is due to recrudescence or to reinfection.