Terapevticheskii arkhiv · 2004
[Helicobacter pylori and stomach adenoma in outpatient practice].
СтатьяНазвание и аннотация: Оригинал на русском
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Minushkin O N, Burdina E G
Аннотация
AIM: To study the role of Helicobacter pylori (HP) persistence in generation of gastric mucosa adenoma.
MATERIAL AND METHODS: Esophagogastroduodenoscopy with biopsy of the mucosa from the antral portion and body of the stomach was made for diagnosis of HP and morphological changes in 28 patients aged 47 to 86 years with gastric adenoma.
RESULTS: Chronic gastritis with HP was diagnosed in 57.1% patients. HP contamination was, as a rule, weak (32.1%) or moderate (53.5%). It correlated with activity of inflammatory and dystrophic changes (the first degree--35.7%, the second one--39.3%; atrophy--99.6%, metaplasia--92.8%, respectively).
CONCLUSION: The morphological study revealed a strong correlation between gastric adenomas and HP persistence. As adenomas are characterized by a high risk of malignant transformation and must be removed, it is recommended to eradicate HB infection.
MATERIAL AND METHODS: Esophagogastroduodenoscopy with biopsy of the mucosa from the antral portion and body of the stomach was made for diagnosis of HP and morphological changes in 28 patients aged 47 to 86 years with gastric adenoma.
RESULTS: Chronic gastritis with HP was diagnosed in 57.1% patients. HP contamination was, as a rule, weak (32.1%) or moderate (53.5%). It correlated with activity of inflammatory and dystrophic changes (the first degree--35.7%, the second one--39.3%; atrophy--99.6%, metaplasia--92.8%, respectively).
CONCLUSION: The morphological study revealed a strong correlation between gastric adenomas and HP persistence. As adenomas are characterized by a high risk of malignant transformation and must be removed, it is recommended to eradicate HB infection.