Pancreas · 2025
Investigation of Geospatial Disparities in Chronic Pancreatitis Outcomes.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Kahan Tamara F, Noriega Marco, Liyen-Cartelle Anabel, Bocchino Rachel, Anderson Kelsey, Zuberi Shaharyar A, Shah Ishani, Olivares Miriam, Kelly Jill, Freedman Steven D, Rabinowitz Loren, Chhoda Ankit, Sheth Sunil G
Аннотация
OBJECTIVES: Chronic pancreatitis (CP) is a fibro-inflammatory disorder characterized by abdominal pain and pancreatic insufficiency resulting in significant morbidity. This study evaluates the impact of geospatial parameters assessed using the Social Vulnerability Index (SVI) on CP outcomes.
MATERIALS AND METHODS: We retrospectively analyzed CP patients with available addresses followed at our pancreas center. We reviewed demographics, number of CP flares, local complications, healthcare-resource utilization, and outpatient opioid prescriptions. Regression analysis was performed to assess the association between outcomes and SVI (divided into 4 quartiles [I-IV; IV being most vulnerable]).
RESULTS: Among 324 CP patients followed over 8 years, we noted trends of higher dependence on governmental insurance or no insurance among patients in higher SVI quartiles (III/IV vs I/II) but no differences in demographics, comorbidities, or etiology of CP. Among patients in higher SVI quartiles, we noted significantly higher frequency of hospitalizations for CP flares and reduced opioid use. Rates of exocrine and endocrine pancreatic dysfunction and healthcare-resource utilization were similar across SVI quartiles.
CONCLUSIONS: Residence in the most vulnerable neighborhoods may be associated with reduced opioid use and more frequent CP flares, suggesting possible inadequate pain control in these patients. These findings should guide prospective investigation of the impact of geospatial social determinants of health in CP.
MATERIALS AND METHODS: We retrospectively analyzed CP patients with available addresses followed at our pancreas center. We reviewed demographics, number of CP flares, local complications, healthcare-resource utilization, and outpatient opioid prescriptions. Regression analysis was performed to assess the association between outcomes and SVI (divided into 4 quartiles [I-IV; IV being most vulnerable]).
RESULTS: Among 324 CP patients followed over 8 years, we noted trends of higher dependence on governmental insurance or no insurance among patients in higher SVI quartiles (III/IV vs I/II) but no differences in demographics, comorbidities, or etiology of CP. Among patients in higher SVI quartiles, we noted significantly higher frequency of hospitalizations for CP flares and reduced opioid use. Rates of exocrine and endocrine pancreatic dysfunction and healthcare-resource utilization were similar across SVI quartiles.
CONCLUSIONS: Residence in the most vulnerable neighborhoods may be associated with reduced opioid use and more frequent CP flares, suggesting possible inadequate pain control in these patients. These findings should guide prospective investigation of the impact of geospatial social determinants of health in CP.