Venous thrombectomy: Device landscape and applications.

Percutaneous mechanical thrombectomy (PMT) has emerged as a prominent treatment option for venous thromboembolism, offering advantages over catheter-directed thrombolysis and anticoagulation therapy, such as reduced bleeding risk and faster thrombus resolution. PMT devices operate through three main mechanisms: aspiration to directly extract thrombi, mechanical fragmentation to break thrombi into smaller pieces, and rheolytic disruption using high-pressure saline jets to dislodge and remove thrombi. This review summarizes the modern PMT device landscape, technical specifications, and indications while exploring extended and off-label uses and highlighting its expanding clinical applications.