JHLT open · 2024
Outcomes after lung transplantation performed using elective cardiopulmonary bypass: A single-center experience.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Blanding Walker M, Hill Morgan A, Hashmi Z A, Huang Kevin X, Whelan Timothy P M, Paoletti Luca, Engelhardt Kathryn E, Gibney Barry C
Аннотация
BACKGROUND: There remains significant variability in the use of intraoperative mechanical circulatory support in lung transplantation. This report details our outcomes using elective cardiopulmonary bypass (CPB) in lung transplantation.
METHODS: We performed a single institution analysis of consecutively enrolled patients who underwent isolated lung transplantation between August 2020 and April 2023. Primary outcomes included rates of grade 3 primary graft dysfunction (PGD) and 1-year survival.
RESULTS: Forty consecutive lung transplants were performed on CBP over the study period. The average PaO2/FiO2 at 72 hours was 369.7 ± 121.4, with grade 3 PGD occurring in 2 patients (5%). The median intraoperative packed red blood cell transfusion requirement was 300 (93.75-727.5) ml. Freedom from nonelective reoperation was 82.5% (n = 33). Mortality was 0% at 90 days, and 1-year survival was 90.5%.
CONCLUSIONS: Lung transplantation can be safely performed with elective CPB support.
METHODS: We performed a single institution analysis of consecutively enrolled patients who underwent isolated lung transplantation between August 2020 and April 2023. Primary outcomes included rates of grade 3 primary graft dysfunction (PGD) and 1-year survival.
RESULTS: Forty consecutive lung transplants were performed on CBP over the study period. The average PaO2/FiO2 at 72 hours was 369.7 ± 121.4, with grade 3 PGD occurring in 2 patients (5%). The median intraoperative packed red blood cell transfusion requirement was 300 (93.75-727.5) ml. Freedom from nonelective reoperation was 82.5% (n = 33). Mortality was 0% at 90 days, and 1-year survival was 90.5%.
CONCLUSIONS: Lung transplantation can be safely performed with elective CPB support.