BMC biology · 2026
Dynamic interplay of maternal and paternal contributions to offspring phenotype in Eurasian perch.
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Debernardis Rossella, Panda Abhipsa, Wałdowska Sylwia, Palińska-Żarska Katarzyna, Klopp Christophe, de Almeida Taina Rocha, Jarmołowicz Sylwia, Hliwa Piotr, Żarski Daniel
Аннотация
BACKGROUND: Parental contributions to offspring phenotype extend beyond genetic inheritance, encompassing non-genetic factors that influence early development. However, the interplay between maternal and paternal effects remains poorly understood. This study investigates these contributions in Eurasian perch (Perca fluviatilis) - a valuable model to study parental effect in finfishes - by analyzing early life traits and transcriptomic profiles of larvae resulting from crosses between wild and domesticated parents.
RESULTS: Maternal effects dominated key developmental traits, including hatching success, growth, and swim bladder inflation. Transcriptomic analysis revealed a complex regulatory interplay, with 573 genes under exclusive maternal control, while no genes were solely influenced by paternal input. Maternal-effect genes were primarily associated with metabolic, developmental, and stress-response pathways, shaping early larval physiology. Further analysis identified Eurasian-perch-specific candidate maternal-effect genes, such as crtac1, slc16a7, cox5b, kdr, cald1, and bin2, highlighting their potential role in early development. Although paternal contributions were limited, a subset of genes exhibited conditional paternal influence, suggesting a nuanced parental interplay in gene expression regulation.
CONCLUSIONS: These findings challenge the traditional perspective of strictly coordinated parental contributions, instead revealing a dynamic parental interplay over gene expression and offspring traits. The dominance of maternal effects suggests a primary role in shaping early development, while paternal factors may modulate expression patterns in a context-dependent manner. This study enhances our understanding of parental effects in fish, providing valuable insights for aquaculture breeding strategies and evolutionary biology research.
RESULTS: Maternal effects dominated key developmental traits, including hatching success, growth, and swim bladder inflation. Transcriptomic analysis revealed a complex regulatory interplay, with 573 genes under exclusive maternal control, while no genes were solely influenced by paternal input. Maternal-effect genes were primarily associated with metabolic, developmental, and stress-response pathways, shaping early larval physiology. Further analysis identified Eurasian-perch-specific candidate maternal-effect genes, such as crtac1, slc16a7, cox5b, kdr, cald1, and bin2, highlighting their potential role in early development. Although paternal contributions were limited, a subset of genes exhibited conditional paternal influence, suggesting a nuanced parental interplay in gene expression regulation.
CONCLUSIONS: These findings challenge the traditional perspective of strictly coordinated parental contributions, instead revealing a dynamic parental interplay over gene expression and offspring traits. The dominance of maternal effects suggests a primary role in shaping early development, while paternal factors may modulate expression patterns in a context-dependent manner. This study enhances our understanding of parental effects in fish, providing valuable insights for aquaculture breeding strategies and evolutionary biology research.