Immunotherapy in Allergic and Mixed Rhinitis.

Allergen immunotherapy is the only treatment modality that can modify severity of allergic rhinitis. Subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) are both effective treatment options. SLIT has a better safety profile with rare reports of systemic reaction events. In this article, we will review evidence pertaining to efficacy of individual treatment allergens and assess relative efficacy and safety of SLIT versus SCIT.