Profiles of drug substances, excipients, and related methodology · 2024
Degradation of fenamates.
СтатьяОбзорНазвание и аннотация: Перевод пока не подготовлен
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Kazi Sadia Hafeez, Sheraz Muhammad Ali, Ahmed Sofia, Anwar Zubair
Аннотация
Fenamates are the most crucial non-steroidal anti-inflammatory drugs (NSAIDs) used to treat pain-related diseases. The clinically prescribed drugs of the fenamate group include mefenamic acid, tolfenamic acid, meclofenamic acid, flufenamic acid, and niflumic acid. Due to their widespread use, all these drugs are considered as the most common water and sewerage pollutants. Studies have been performed to remove these contaminants from water sources by various forced degradation procedures, but the number of studies in this area is limited. In this chapter, an effort has been made to review the degradation of multiple fenamates in different systems and the factors affecting the degradation rates with the proposed degradation pathways.