Internal medicine (Tokyo, Japan) · 2007
Comparison of the incidence of acute coronary event after balloon angioplasty vs. stenting in native coronary arteries.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Goto Kenji, Shiode Nobuo, Shirota Kinya, Ishii Hiroshige, Suenari Kazuyoshi, Sairaku Akinori, Mikami Shinsuke, Kato Yasuko
Аннотация
OBJECTIVES: We sought to determine the incidence of acute coronary events after coronary stenting in comparison to that after plain old balloon angioplasty (POBA).
BACKGROUND: Although coronary stenting is proven to be effective in reducing the incidence of restenosis, the long-term outcome in terms of acute coronary events has not been clarified.
METHODS: Study subjects were 1,507 patients with 2,780 native coronary artery lesions treated by POBA (n=1,400) or stenting (n=1,380). Lesion stabilization, which was defined as freedom from restenosis confirmed by follow-up angiography 3 months after POBA and 6 months after stenting, was achieved in all subjects. All patients were clinically monitored for symptoms for at least 1 year after angioplasty, and the incidence of angiographically confirmed acute coronary event was compared between groups.
RESULTS: The clinical follow-up period was significantly longer in the POBA group than in the stent group (8.4 +/- 5.0 years vs. 5.9 +/- 3.0 years, p<0.0001). Acute coronary events occurred in association with 32 lesions (1.2% overall); the incidence was 1.1% (15 of 1,400) after POBA and 1.2% (17 of 1,380) after stenting. Freedom from acute coronary events related to the treated lesions was similar between the two groups. (p=0.0518 by log-rank test).
CONCLUSION: In terms of acute coronary events, the long-term clinical outcome of stenting is equivalent to that of POBA.
BACKGROUND: Although coronary stenting is proven to be effective in reducing the incidence of restenosis, the long-term outcome in terms of acute coronary events has not been clarified.
METHODS: Study subjects were 1,507 patients with 2,780 native coronary artery lesions treated by POBA (n=1,400) or stenting (n=1,380). Lesion stabilization, which was defined as freedom from restenosis confirmed by follow-up angiography 3 months after POBA and 6 months after stenting, was achieved in all subjects. All patients were clinically monitored for symptoms for at least 1 year after angioplasty, and the incidence of angiographically confirmed acute coronary event was compared between groups.
RESULTS: The clinical follow-up period was significantly longer in the POBA group than in the stent group (8.4 +/- 5.0 years vs. 5.9 +/- 3.0 years, p<0.0001). Acute coronary events occurred in association with 32 lesions (1.2% overall); the incidence was 1.1% (15 of 1,400) after POBA and 1.2% (17 of 1,380) after stenting. Freedom from acute coronary events related to the treated lesions was similar between the two groups. (p=0.0518 by log-rank test).
CONCLUSION: In terms of acute coronary events, the long-term clinical outcome of stenting is equivalent to that of POBA.