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DOI 10.1186/s12903-025-05564-8

Медицинская библиотека · BMC oral health · 2025

Investigating the effect of propolis-containing chewing gum in comparison with propolis-containing mouthwash on reducing gingival inflammation in patients with gingivitis.

Khabazian Arezou, Mirhashemi Fatemeh Sadat, Sadeghi Faezeh

СтатьяРандомизированное исследованиеСравнительное исследованиеПеревод пока не подготовлен

Аннотация

BACKGROUND

The aim of this parallel clinical trial is to investigate the effectiveness of propolis-containing chewing gum and mouthwash in reducing gingival inflammation in patients with gingivitis referred to the Periodontology Department of Yazd Dental School in 2022.

METHODS

For this purpose, a total of 20 patients were randomly assigned to either the mouthwash group or the chewing gum group. Plaque index (PI), papillary bleeding index (PBI), and gingival index (GI) were recorded before and after one week of using the assigned product, followed by scaling and root planing (SRP). Statistical analysis was performed using Chi-square, T-Test, Mann-Whitney, Paired Samples, and Wilcoxon Signed Ranks tests.

RESULTS

Both groups showed significant reduction in PI (p-value = 0.0001), PBI (p-value = 0.0001), and GI (p-value = 0.003 for chewing gum group and p-value = 0.006 for mouthwash group). There was no significant difference between the two groups in terms of PI (p-value = 0.686), PBI (p-value = 0.737), and GI (p-value = 1.000).

CONCLUSION

It can be concluded that both propolis-containing chewing gum and mouthwash can effectively reduce dental plaque, papillary bleeding, and gingival inflammation in patients with gingivitis. No significant difference was observed between the two products in terms of effectiveness.

TRIAL REGISTRATION: The study was registered at IRCT (IRCT20220420054592N1).It was retrospectively registered on 11/6/2022.

Для цитирования: Khabazian Arezou, Mirhashemi Fatemeh Sadat, Sadeghi Faezeh. Investigating the effect of propolis-containing chewing gum in comparison with propolis-containing mouthwash on reducing gingival inflammation in patients with gingivitis.. BMC oral health. 2025. DOI: 10.1186/s12903-025-05564-8.

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