Pediatric pulmonology · 2026
Home Non-Invasive Ventilation as an Alternative to Tracheostomy in Infants With Moderate-to-Severe Bronchopulmonary Dysplasia: A Retrospective Cohort Study.
СтатьяСравнительное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Mundi Kudrat, Kieran Emily, Dyk Jessie Van, Wen Emma, Wright Marie
Аннотация
BACKGROUND AND OBJECTIVE: Improved survival among extremely preterm infants has increased the prevalence of bronchopulmonary dysplasia (BPD) requiring respiratory support after neonatal intensive care unit (NICU) discharge. This study aimed to evaluate temporal trends in home respiratory support practices and compare clinical outcomes between infants with BPD discharged on supplemental oxygen, non-invasive positive airway pressure (NI-PAP), and tracheostomy ventilation (TV). We hypothesized that home NI-PAP is a feasible alternative to TV in appropriately selected infants, with comparable growth and neurodevelopmental outcomes and lower healthcare utilization.
METHODS: Retrospective cohort study of infants born at <32 weeks' gestation and discharged from a Level IV or III NICU in British Columbia between 2013 and 2022 on supplemental oxygen, NI-PAP, or TV for BPD management. Patient characteristics, healthcare utilization, and duration of support were described. Longitudinal growth and neurodevelopmental outcomes were compared using adjusted linear mixed-effects models.
RESULTS: Among 102 infants, 52% received supplemental oxygen, 39% NI-PAP, and 9% TV. NI-PAP use increased over time, while tracheostomy use declined. Infants on NI-PAP were discharged earlier, were younger at respiratory support discontinuation, and had fewer hospital readmissions than those receiving TV. Infants requiring TV had lower neurodevelopmental scores. Growth trajectories were similar.
CONCLUSIONS: In this cohort of infants with BPD requiring home respiratory support, NI-PAP use increased over time and was associated with shorter hospitalization and lower healthcare utilization compared with TV. Differences in outcomes likely reflect differences in disease severity and clinical complexity. NI-PAP may represent an appropriate management strategy for selected infants with moderate-to-severe BPD.
METHODS: Retrospective cohort study of infants born at <32 weeks' gestation and discharged from a Level IV or III NICU in British Columbia between 2013 and 2022 on supplemental oxygen, NI-PAP, or TV for BPD management. Patient characteristics, healthcare utilization, and duration of support were described. Longitudinal growth and neurodevelopmental outcomes were compared using adjusted linear mixed-effects models.
RESULTS: Among 102 infants, 52% received supplemental oxygen, 39% NI-PAP, and 9% TV. NI-PAP use increased over time, while tracheostomy use declined. Infants on NI-PAP were discharged earlier, were younger at respiratory support discontinuation, and had fewer hospital readmissions than those receiving TV. Infants requiring TV had lower neurodevelopmental scores. Growth trajectories were similar.
CONCLUSIONS: In this cohort of infants with BPD requiring home respiratory support, NI-PAP use increased over time and was associated with shorter hospitalization and lower healthcare utilization compared with TV. Differences in outcomes likely reflect differences in disease severity and clinical complexity. NI-PAP may represent an appropriate management strategy for selected infants with moderate-to-severe BPD.