Construction of quaternary alkyl motifs through palladium-catalyzed oxidative coupling of 1,3-dicarbonyl compounds with alkenes followed by C-C bond cleavage.

A palladium-catalyzed coupling reaction has been developed for the generation of tertiary alkylation products by reacting olefins with diversely functionalized 1,3-dicarbonyls. The reaction involves the tertiary C-H alkylation of 1,3-dicarbonyls with olefins to produce a tertiary alcohol, followed by C-C bond cleavage.