[Recurrence of hypertrophic osteoarthropathy (Pierre-Marie-Bamberger syndrome) as the first clinical indication of a second lung cancer 10 years after initial diagnosis].

Hypertrophic osteoarthropathy, also known as "Pierre-Marie-Bamberger syndrome," is a rare syndromic disease and, as a paraneoplastic syndrome, often associated with non-small cell lung cancer (NSCLC). Symptoms include arthritic complaints such as joint pain, which can worsen with movement, and swelling, as well as drumstick fingers and watch glass nails. We herein report on a patient in who not only the recognition of the paraneoplastic syndrome of hypertrophic osteoarthropathy had led to the early diagnosis of non-small cell lung carcinoma (NSCLC) and curative surgery 10-years ago, but in who recently, after a so far recurrence-free interval, the recurrence of the known nail changes enabled for early diagnosis of a second carcinoma, which was also successfully treated surgically.