Globule leukocyte tumor involving the small intestine in a cat.

Globule leukocyte tumor involving the distal portion of the jejunum and proximal portion of the ileum caused chronic vomiting and weight loss in a 3-year-old cat. The intestinal mass was resected during exploratory laparotomy. The histologic appearance of the mass was characterized by inclusion of numerous intracytoplasmic eosinophilic granules. Similar cells were found in the mesenteric lymph node and were suggestive of metastasis. Tumor recurrence was not detected until 13.5 months after the surgery. The malignant but slow-growing nature of this tumor allowed a disease-free interval that exceeded 1 year, despite incomplete tumor resection.