BMJ (Clinical research ed.) · 2025

FUTURE-AI: international consensus guideline for trustworthy and deployable artificial intelligence in healthcare.

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Lekadir Karim, Frangi Alejandro F, Porras Antonio R, Glocker Ben, Cintas Celia, Langlotz Curtis P, Weicken Eva, Asselbergs Folkert W, Prior Fred, Collins Gary S, Kaissis Georgios, Tsakou Gianna, Buvat Irène, Kalpathy-Cramer Jayashree, Mongan John, Schnabel Julia A, Kushibar Kaisar, Riklund Katrine, Marias Kostas, Amugongo Lameck M, Fromont Lauren A, Maier-Hein Lena, Cerdá-Alberich Leonor, Martí-Bonmatí Luis, Cardoso M Jorge, Bobowicz Maciej, Shabani Mahsa, Tsiknakis Manolis, Zuluaga Maria A, Fritzsche Marie-Christine, Camacho Marina, Linguraru Marius George, Wenzel Markus, De Bruijne Marleen, Tolsgaard Martin G, Goisauf Melanie, Cano Abadía Mónica, Papanikolaou Nikolaos, Lazrak Noussair, Pujol Oriol, Osuala Richard, Napel Sandy, Colantonio Sara, Joshi Smriti, Klein Stefan, Aussó Susanna, Rogers Wendy A, Salahuddin Zohaib, Starmans Martijn P A, FUTURE-AI Consortium

Аннотация

Despite major advances in artificial intelligence (AI) research for healthcare, the deployment and adoption of AI technologies remain limited in clinical practice. This paper describes the FUTURE-AI framework, which provides guidance for the development and deployment of trustworthy AI tools in healthcare. The FUTURE-AI Consortium was founded in 2021 and comprises 117 interdisciplinary experts from 50 countries representing all continents, including AI scientists, clinical researchers, biomedical ethicists, and social scientists. Over a two year period, the FUTURE-AI guideline was established through consensus based on six guiding principles—fairness, universality, traceability, usability, robustness, and explainability. To operationalise trustworthy AI in healthcare, a set of 30 best practices were defined, addressing technical, clinical, socioethical, and legal dimensions. The recommendations cover the entire lifecycle of healthcare AI, from design, development, and validation to regulation, deployment, and monitoring.

FUTURE-AI: international consensus guideline for trustworthy and deployable artificial intelligence in healthcare.

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