[Effect of the observance of diurnal fast of Ramadan on duodenal ulcer healing with lansoprazole. Results of a prospective controlled study].

OBJECTIVES

The aims of this study were: a) to determine whether patients with duodenal ulcer treated with a proton pump inhibitor may fast during the month of Ramadan, b) to evaluate the result of the treatment in this condition.

METHODS

Fifty-seven patients with acute duodenal ulcer confirmed by endoscopy were included in the study. All the patients received 30 mg lansoprazole per day during 4 weeks. After randomization, patients of group I (n = 27) were dispensed from fasting, while those of group II (n = 30) fasted. Endoscopy was performed at the end of the month of the fast.

RESULTS

The course of symptoms was not different in groups I and II. There were no ulcer complications. Healing rates at endoscopy were 88.8% and 90% in groups I and II, respectively. Fasting had no influence on the result of duodenal ulcer treatment by lansoprazole which was well tolerated.

CONCLUSION

Patients with duodenal ulcer treated with lansoprazole may fast without running any risk.