[Capillary hyperpermeability syndrome of the face].

BACKGROUND

Capillary leak syndrome is a rare disorder, with various clinical features, characterized by episodes of diffuse edema.

CASE REPORT: We report the case of a 83 year-old woman with capillary leak syndrome of the face characterized by recurrent episodes of edamata. We found a follicular non-Hodgkin's lymphoma and high levels of plasma interleukin (IL) 2 and IL 6. Regression of edema and remission of hematology disease have been obtained with corticoids and chloraminophene.

DISCUSSION: This case illustrates that capillary leak syndrome may present as an edema of the face and may be in some cases considered as a paraneoplastic syndrome. The role of cytokines seems important. This case suggests that corticoids may be useful in the management of neoplasm induced capillary leak syndrome.