A case of CD45-negative diffuse large B-cell lymphoma in thyroid gland.

CD45, also referred to as the leukocyte common antigen (LCA), is selectively expressed on nucleated hematopoietic cells in healthy individuals. It is also widely expressed in various types of hematologic malignancies--although 10% of acute lymphoblastic leukemia and more than 50% of multiple myeloma have been reported to lack its expression. In this paper, we report a rare case of CD45-negative non-Hodgkin's lymphoma (NHL) that affected the thyroid gland.