MedElevator
Войти в исследования Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2011
[Expression of psoriasin in mycosis fungoides and its significance].
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Xu Lei, Zeng Wei-hui, Zheng Yan
Аннотация
OBJECTIVE: To investigate the role of psoriasin in mycosis fungoides.
METHODS: Psoriasin protein expressions in normal skin tissues and mycosis fungoides tissues were detected by immunohistochemistry.
RESULTS: Psoriasin protein was not expressed in normal skin tissues. In 21 mycosis fungoides tissue specimens, psoriasin was expressed in the stratum corneum and stratum spinosum but not in the stratum basale, with a positivity rate of 90.5% in these specimens. Psoriasin expression was significantly higher in mycosis fungoidesa tissues than in normal tissues (P<0.001).
CONCLUSION: Psoriasin may play a role in the pathogenesis of mycosis fungoides by chemotaxis of CD4+ T lymphocytes.
METHODS: Psoriasin protein expressions in normal skin tissues and mycosis fungoides tissues were detected by immunohistochemistry.
RESULTS: Psoriasin protein was not expressed in normal skin tissues. In 21 mycosis fungoides tissue specimens, psoriasin was expressed in the stratum corneum and stratum spinosum but not in the stratum basale, with a positivity rate of 90.5% in these specimens. Psoriasin expression was significantly higher in mycosis fungoidesa tissues than in normal tissues (P<0.001).
CONCLUSION: Psoriasin may play a role in the pathogenesis of mycosis fungoides by chemotaxis of CD4+ T lymphocytes.