Intraocular T-cell lymphoma due to mycosis fungoides and response to intravitreal methotrexate.

PURPOSE: To report a case of mycosis fungoides with subsequent intraocular involvement and good response to intravitreal methotrexate.

DESIGN

Case report.

METHODS

Retrospective chart review.

RESULTS

This is a rare case of intraocular T-cell lymphoma due to mycosis fungoides, which responded to intravitreal methotrexate therapy in a previous vitrectomized eye.

CONCLUSIONS

Intraocular T-cell lymphoma is a rare manifestation of mycosis fungoides and should be considered in the differential diagnosis of chronic uveitis in patients with this history. Intravitreal methotrexate may be an effective adjunctive treatment for this condition.