Research evidence review and appraisal: pediatric central venous catheter care bundling.

Central venous catheters are integral to the care of acutely ill children, providing reliable vascular access for infusions, hemodynamic monitoring, and blood sampling. However, there are risks associated with their use, the most common of which is central line-associated blood stream infections. These infections result in increased lengths of stay, increased costs, and high mortality rates. A thorough review of research evidence has been completed to fully appreciate the state of the evidence regarding the effects of bundling together the care for central venous catheters, and practice recommendations have been provided. Published studies have been appraised and evaluated for clinical and statistical significance. This appraisal has resulted in clear and specific recommendations for evidence-based practice applications, and potential policy implications are outlined in this article.