Renal failure in Wegener's granulomatosis: recovering following dialysis and cyclophosphamide-prednisone therapy.

Two patients with Wegener's granulomatosis, crescentic glomerulonephritis, and severe renal failure are described. Both patients required hemodialysis for control of uremic symptoms. Cyclophosphamide-prednisone therapy successfully controlled the extra-renal manifestations of their disease and reversed the renal failure so that dialysis could be discontinued.