[Relation between psychological symptoms and gynecological, hormonal and perimenopausal disorders].

This works consists of two parts. In the first part an epidemiological and diagnostic study is made of all the patients of climacteric age attended during a period of four years. One group is separated that reveals a similar psychopathological picture and by means of a process of statistical association you continue relating significantly to the gynecological-hormonal alterations that patients present. A subgroup is isolated that shows the highest probability of a significant association between the psychopathological picture and perimenopausal neurohormonal changes. In the second part an open clinical study is made of twenty patients who belong to the final subgroup resulting from the previous part. Two samples are made with ten patients in each. One of these samples is treated with standard psychopharmacological medication. The other sample is treated with a centrally acting drug with repercussions mainly on the neurovegetative climacteric alterations. A symptomatological improvement is shown un the second sample of patients that is significantly higher, a result which supports the hypothesis in the first part, concerning the final subgroup and the organic alterations characteristics of the climacteric.