Prescribing patterns and comparison of culture versus empiric-based selection of meropenem in cats and dogs in a veterinary teaching hospital (2011-2018).

The utilization of meropenem in a small animal veterinary teaching hospital over a 7-year period was retrospectively analyzed, and culture (CBD) versus empiric-based decisions (EBD) were compared. Meropenem was infrequently prescribed at a rate of 0.50 prescriptions/1000 admissions in cats and 0.58/1000 in dogs. The most common condition for meropenem prescription in both cats and dogs was septic peritonitis (15/52, 28.8%). Overall 65.4% of meropenem prescriptions were initiated without, or prior to, culture results indicating a need for the drug. Based on retrospective analysis of culture and susceptibility results, only 2.9% of empirical meropenem selections were indicated, while the majority were not indicated (52.9%), or of questionable indication (44.2%).