[Glandular-squamous cell stomach cancer].

Five cases of adenosquamous carcinoma in the body of the stomach and pyloric antrum are presented. These cases account for 0.15% of the surgical interventions performed in the Center from 1952 to 1985. No specific macroscopic features and clinical manifestations different from those of common adenocarcinoma were revealed. A microscopic study evidenced for a combination of squamous cell and glandular cancer varying in the differentiation degree and quantitative proportion of the components. Electron-microscopically, signs of squamous cell differentiation were found in 11 out of 53 cases of gastric carcinoma. Some of them had tumor cells exhibiting both glandular and squamous epithelium elements suggesting that both the structures originate from cambial multipotent cells of gastric mucosa.