Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 1997
[Efficacy of a triclosan/copolymer dentifrice in the control of plaque and gingivitis: a six-month study in China].
Клиническое исследованиеАннотация на английскомСтатьяРандомизированное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Hu D, Zhang J, Wan H, Zhang Y, Volpe A R, Petrone M E
Аннотация
A total of one hundred fifty three healthy male and female adults were entered into a six month, double-blind clinical study designed to evaluate the effect of a dentifrice containing 0.3% triclosan and 2.0% PVM/MA copolymer in a 0.243% sodium fluoride/silica base, relative to a 0.243% sodium fluoride silica base control dentifrice on supragingival plaque accumulation and gingivitis. Plaque and gingivitis were scored after 3 and 6 months' use of the assigned dentifrice. At the end of the study, the dentifrice containing triclosan/copolymer demonstrated an average reduction, relative to the control dentifrice of 16.1% in plaque accumulation and 24.3% in gingivitis. Both were statistically significant(P < 0.001). It was concluded that the twice-daily use of the triclosan/copolymer containing dentifrice resulted in a significant reduction in plaque formation and a significant improvement in gingival health. No side-effects were observed.