Concurrence of multiple sclerosis and primary biliary cholangitis: Report of 3 cases.

BACKGROUND

Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system which damages the myelin and axon. Primary biliary cholangitis (PBC) is a slow progressive liver disease with autoimmune feature in which non-purulent destructive cholangitis and interlobular bile duct destruction occur. Involvement of each of PBC and MS is thought to be related to environmental exposure in genetically susceptible persons.

CASE PRESENTATION: Here, we aim to report 3 women 52, 27 and 51 years old with MS and PBC.

CONCLUSION

Although MS seems to have an association with some autoimmune gastrointestinal disorders such as ulcerative colitis, the concurrence of MS and PBC has been rarely reported.