[Enzyme activity of the gastric mucosal antioxidant system during hypoxia].

The activity of enzymes of the antioxidant system and pO2 in the gastric mucosa (GM) was studied in patients with gastric ulcer. The various enzymes differed in activity. Along with low activity of superoxide dismutase (SOD), glutathione peroxidase (GP), and glutathione reductase (GR), both normal and increased values were encountered. In GM hypoxia the GP activity increased in the peri-ulcerous zone. There was no statistically significant increase of SOD activity and reduction of GR activity.