[The pathogenetic role of dysbacteriosis of the large intestine in the recurrence of peptic ulcer].

Microbiologic investigations were carried out of excrements as were measurements of blood levels of malonic dialdegyde, reduced glutathione and activity of glutathione-dependent enzymes in 36 patients with peptic ulcer when they experienced exacerbation. Gastric and duodenal ulcer in exacerbation was accompanied by dysbacteriosis of the large intestine, uncontrolled augmentation of the processes of free-radical lipid oxidation against the background of impairment of functional systems of antiradical defence, which fact plays its part in relapsing of gastroduodenal ulcer.