Медицинская библиотека · Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2012

T2 glottic carcinoma: analysis of recurrences in 36 cases undergoing primary transoral laser microsurgery resection.

Rigby Matthew H, Reynolds Luke F, Hart Robert D, Trites Jonathan R B, Brown Tim, Mark Taylor S

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Аннотация

OBJECTIVE

Between 2002 and 2008, over 100 patients with glottic carcinoma have undergone transoral laser microsurgical (TLM) resection at the QEII Health Sciences Centre in Halifax, Nova Scotia. The objective of this study was to assess the oncologic outcomes for all cases staged as T2 in this cohort.

METHODS

A prospective database was developed to monitor outcomes. All 36 cases of primary T2 glottic carcinoma were selected from the database for analysis. Kaplan-Meier survival analyses evaluated the following end points at 36 months: overall survival, disease-specific survival, and local control and disease-free survival with one procedure.

RESULTS

The Kaplan-Meier estimates of 36-month outcomes were 89% (SE 6.0%) overall survival and disease-specific survival, 81% (SE 7.1%) local control with one procedure, and 70% (SE 8.0%) disease-free survival with one procedure.

CONCLUSIONS

The observed 36-month outcomes support the use of TLM as the primary treatment modality for T2 glottic cancers.

Для цитирования: Rigby Matthew H, Reynolds Luke F, Hart Robert D, Trites Jonathan R B, Brown Tim, Mark Taylor S. T2 glottic carcinoma: analysis of recurrences in 36 cases undergoing primary transoral laser microsurgery resection.. Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale. 2012.

Предметные рубрики MeSH

Aged Aged, 80 and over Female Glottis Humans Incidence Laryngeal Neoplasms Laryngectomy Laser Therapy Male Microsurgery Middle Aged Natural Orifice Endoscopic Surgery Neoplasm Recurrence, Local Neoplasm Staging Nova Scotia Prospective Studies Survival Rate Treatment Outcome

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