Current HIV/AIDS reports · 2025
Envisioning a Multidisciplinary HBV Cure Research Agenda.
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Dubé Karine, Ahmed Ali, Cohen Chari, Ibrahim Yasmin, Yendewa George A, Cachay Edward R, Wang Su, Marks Kristen, Kim Arthur Y, Sugarman Jeremy, Thomas David L, Thio Chloe L, Bhattacharya Debika
Аннотация
PURPOSE OF REVIEW: We examine the current understanding of the multidisciplinary aspects of hepatitis B cure research, such as socio-behavioral sciences, ethics, community engagement, and translational and implementation science.
RECENT FINDINGS: The peer-reviewed literature on the multi-disciplinary aspects of HBV cure research is gradually expanding, although several areas still require attention. These deficiencies include: the acceptability of HBV treatment discontinuations, HBV-related stigma, the impact of co-infections (e.g., HIV), and the translation of discoveries to resource-limited settings. This review highlights the importance of a multidisciplinary framework that bridges socio-behavioral sciences, ethics, community engagement, and translational and implementation science to help ensure the development of an effective, acceptable, scalable and equitable HBV cure.
RECENT FINDINGS: The peer-reviewed literature on the multi-disciplinary aspects of HBV cure research is gradually expanding, although several areas still require attention. These deficiencies include: the acceptability of HBV treatment discontinuations, HBV-related stigma, the impact of co-infections (e.g., HIV), and the translation of discoveries to resource-limited settings. This review highlights the importance of a multidisciplinary framework that bridges socio-behavioral sciences, ethics, community engagement, and translational and implementation science to help ensure the development of an effective, acceptable, scalable and equitable HBV cure.