Characteristics of the Management of Gastric and Duodenal Ulcers in Individuals With Advanced Chronic Kidney Disease.

Peptic ulcer disease in patients with end -stage chronic kidney disease presents a complex clinical problem due to metabolic disturbances, impaired mucosal regeneration, polypharmacy, and limitations in the use of standard medications. In this study, we conducted a comparative analysis of conservative and surgical (kidney transplant ) management of gastric and duodenal ulcers in patients with end -stage renal disease versus patients without renal dysfunction. Among the 34 patients who were examined, findings showed that kidney transplant contributed to rapid ulcer healing, normalization of biochemical parameters, and reduction in recurrence rates. The study highlighted the necessity of individualized treatment strategies for patients with end -stage renal disease and emphasized the importance of restoring renal function to improve gastrointestinal outcomes.