[An experimental observation of repair after transection of cauda equina fibers in cat].

OBJECTIVE

To explore the regeneration characteristics after cauda equina transection.

METHODS

Fibrin glue was chosen to repair transected left L6,7 roots in cat, and right roots in situ of the transected ends were served as the control. The characteristics of regeneration were observed by immunohistocytochemistry and morphometric analysis.

RESULTS

Regeneration was found not only in site of anastomosis, but also in corresponding spinal segments and DRGs. Sensory and motor evoked potentials (SEP and MEP) performed before and after transection and before taking specimen revealed the course of functional recovery on severed and regenerated nerve roots. The regeneration of moter roots was better than that of sensory roots, and they were mainly blocked at the site of central-peripheral transition zone.

CONCLUSIONS

The method of adhesion by fibrin glue can replace traditional suture, and it is superior to suture.