Functional dyspepsia management: towards earlier consideration of gut-brain-targeted strategies.

This letter comments on a recent article published in the Revista Española de Enfermedades Digestivas (REED) addressing the management of functional dyspepsia in primary care. In the context of a stepwise treatment framework, we suggest that earlier incorporation of gut-brain-targeted and phenotype-based approaches may be considered in selected patients. A more individualized and mechanism-informed strategy may help optimize symptom control and reduce delays in effective therapy.