American journal of ophthalmology · 2004
Intravitreal injections of triamcinolone acetonide for severe vitritis in patients with incomplete Behcet's disease.
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Kramer Michal, Ehrlich Rita, Snir Moshe, Friling Ronit, Mukamel Masha, Weinberger Dov, Axer-Siegel Ruth
Аннотация
PURPOSE: To report our experience with intravitreal triamcinolone acetonide (IVTA) injections for the treatment of sight-threatening vitritis.
DESIGN: Interventional case series.
METHODS: Three patients with acute severe exacerbations of noninfectious panuveitis and vitritis were treated with IVTA injections alone or as an adjunct to systemic immunosuppressive agents.
RESULTS: Rapid clearance of the vitreous inflammation with improvement in visual acuity was observed 1 to 2 weeks after injection. The effect lasted 2 to 6 months, with the shortest duration in the vitrectomized eye of Patient 1. Repeated injections were required in all patients.
CONCLUSION: Intravitreal triamcinolone acetonide may be beneficial in selected cases of vitritis. This treatment modality has a rapid effect and may lower the use of systemic agents.
DESIGN: Interventional case series.
METHODS: Three patients with acute severe exacerbations of noninfectious panuveitis and vitritis were treated with IVTA injections alone or as an adjunct to systemic immunosuppressive agents.
RESULTS: Rapid clearance of the vitreous inflammation with improvement in visual acuity was observed 1 to 2 weeks after injection. The effect lasted 2 to 6 months, with the shortest duration in the vitrectomized eye of Patient 1. Repeated injections were required in all patients.
CONCLUSION: Intravitreal triamcinolone acetonide may be beneficial in selected cases of vitritis. This treatment modality has a rapid effect and may lower the use of systemic agents.