Future oncology (London, England) · 2024
Transfusion-related cost offsets and time burden in patients with myelofibrosis on momelotinib vs. danazol from MOMENTUM.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Masarova Lucia, Verstovsek Srdan, Liu Tom, Rao Sumati, Sajeev Gautam, Fillbrunn Mirko, Simpson Ryan, Li Weilong, Yang Joseph, Le Lorier Yvette, Gorsh Boris, Signorovitch James
Аннотация
Aim: To estimate projected US-based cost and time burden for patients with myelofibrosis and anemia treated with momelotinib compared with danazol.Methods: Cost and time burden were calculated based on the transfusion status of patients in the MOMENTUM trial and estimates extracted from previous studies.Results: Reductions in transfusion associated with momelotinib are projected to result in cost and time savings compared with danazol in transfusion-dependent and transfusion-independent/requiring patients with myelofibrosis, respectively: annual medical costs ($53,143 and $46,455 per person), outpatient transfusion costs ($42,021 and $8,370 per person) and annual time savings (173 and 35 h per person).Conclusion: Fewer transfusions with momelotinib are projected to result in cost and time savings in patients with myelofibrosis and anemia compared with danazol.