Gan to kagaku ryoho. Cancer & chemotherapy · 2018
[Two Cases of Anal Canal Adenocarcinoma with Pagetoid Spread Treated with Laparoscopic Abdominoperineal Resection].
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Ogawa Soichiro, Arita Tomohiro, Nakanishi Masayoshi, Kuriu Yoshiaki, Murayama Yasutoshi, Kudo Michihiro, Kosuga Toshiyuki, Konishi Hirotaka, Morimura Ryo, Shiozaki Atsushi, Ikoma Hisashi, Kubota Takeshi, Fujiwara Hitoshi, Okamoto Kazuma, Otsuji Eigo
Аннотация
Anal canal adenocarcinoma with pagetoid spread has different a treatment strategy and prognosis from extramammary perianal Paget disease. We report two cases of anal canal adenocarcinoma with pagetoid spread along with a literature review. Case 1: A 69-year-old woman complained of perianal pain, redness, and erosion. Biopsy revealed adenocarcinoma with pagetoid spread. Laparoscopic abdominoperineal resection was performed, which resulted in 12 months' survival without postoperative recurrence. Case 2: A 62-year-old man complained of fecal occult blood and hemorrhoid. Under the diagnosis of anal canal cancer, transanal tumor resection was performed. Five years after surgery, he underwent endoscopic submucosal dissection for anal canal cancer. Ten years after surgery, he complained of anal tumor and perianal redness. Biopsy revealed adenocarcinoma with pagetoid spread. Laparoscopic abdominoperineal resection was performed, which resulted in 10 months' survival without postoperative recurrence.