Journal of clinical pharmacy and therapeutics · 2019
Intraperitoneal vancomycin in neonates during peritoneal dialysis: A case report.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Company-Albir María José, García-Robles Ana, Torres-Martinez Ester, Marqués-Miñana María Remedios, Vento-Torres Máximo, Poveda José Luis
Аннотация
WHAT IS KNOWN AND OBJECTIVE: Guidelines for prevention and treatment of peritonitis in paediatric patients recommend vancomycin. We present the clinical practice in neonates during peritoneal dialysis and evaluate dosage and serum levels of vancomycin.
CASE SUMMARY: This case report describes a newborn with acute renal failure under continuous peritoneal dialysis therapy and intraperitoneal vancomycin. We report the treatment dosage and serum vancomycin levels.
WHAT IS NEW AND CONCLUSION: There is great variability in the recommended dose of vancomycin for continuous peritoneal dialysis and the available clinical experience. Further investigation of dosing in children particularly in newborns, especially in loading dose, is necessary.
CASE SUMMARY: This case report describes a newborn with acute renal failure under continuous peritoneal dialysis therapy and intraperitoneal vancomycin. We report the treatment dosage and serum vancomycin levels.
WHAT IS NEW AND CONCLUSION: There is great variability in the recommended dose of vancomycin for continuous peritoneal dialysis and the available clinical experience. Further investigation of dosing in children particularly in newborns, especially in loading dose, is necessary.